Cells Is Mediated by Integrin 1 / GARP Complex on T Regulatory β TGF - 1 from the Latent β Release of Active TGF -

Mediated by Integrin 1 / GARP Complex on T Regulatory β TGF - 1 from the Latent β Release of Active TGF

Integrin 1 / GARP Complex on T Regulatory β TGF - 1 from the Latent β Release of Active TGF -

Integrin 1 / GARP Complex on T Regulatory β TGF - 1 from the Latent β Release of Active TGF - Shevach

GARP Complex on T Regulatory β TGF - 1 from the Latent β Release of Active TGF

Regulation of the Expression of GARP/Latent TGF-b1 Complexes on Mouse T Cells and Their Role in Regulatory T Cell and Th17 Differentiation

GARP/LRRC32 was defined as a marker of activated human regulatory T cells (Tregs) that is responsible for surface localization of latent TGF-b1. We find that GARP and latent TGF-b1 are also found on mouse Tregs activated via TCR stimulation; however, in contrast to human Tregs, GARP is also expressed at a low level on resting Tregs. The expression of GARP can be upregulated on mouse Tregs by IL...